Prevalence of Peripartum Cardiomyopathy in Pre-Eclampsia Patients Presenting To a Tertiary Care Health Facility

Ramal Khalid; Sadia Sheerazi; Javeria Amjad Memon; Rukhsana; Anila Mujadid; Gulfareen Haider

doi:10.71104/jsogp.v15i3.923

Ramal Khalid Women medical officer, Sindh govt. Hospital Koshar, latifabad (Ex. Resident LUMHS)
Sadia Sheerazi Women medical officer, RHC Daur, (Ex. Resident LUMHS)
Javeria Amjad Memon 3 Assistant professor of cardiology Indus Medical College T M khan, (Ex. Resident LUMHS)
Rukhsana Senior Demonstrator of Physiology, Suleman Roshan Medical College Tando Adam
Anila Mujadid Assistant Professor, Gynae and OBS, LUMHS Thatta
Gulfareen Haider Professor of Obs & Gynae, Isra University Hospital Hyderabad

DOI: https://doi.org/10.71104/jsogp.v15i3.923

Keywords: : Peripartum cardiomyopathy, pre-eclamptic women

Abstract

Objective: To determine the frequency of Peripartum cardiomyopathy (PPCM) in Pre-eclamptic women presenting to a tertiary care facility.

Methodology: This descriptive cross-sectional study was conducted over a period of six months, from December 9, 2021, to June 10, 2022, in the Gynecology and Obstetrics Unit I of Liaquat University Hospital, Hyderabad. The study population comprised preeclampsia women aged 18 to 45 years, with a gestational age of more than 20 weeks as confirmed by early ultrasound, regardless of parity, and carrying a single alive fetus. PPCM was diagnosed based on echocardiographic findings, with the key diagnostic criterion being a left ventricular ejection fraction (LVEF) of less than 45%.

Results: Of 102 patients, the mean age of the patients was 25.57 Â±3.73 years. The mean height, weight, and BMI of the patients were 160.11 Â±8.89 cm, 75.09 Â±14.82 kg, and 29.08 Â±5.19 kg/m2 respectively. The mean 24 hours proteinuria level of the patients was 344.62 Â±16.35 mg/24 hours. The mean ejection fraction was found to be 55.01 Â±9.69%. Frequency of PPCM was observed in 9 (9%) patients, which was statistically insignificant according to age, residential status, BMI and mode of delivery (>0.05).

Conclusion: PPCM was concluded to be 9% among pre-eclamptic women, highlighting a notable association between pre-eclampsia and the development of cardiac dysfunction during the peripartum period, which underscoring the need for enhanced clinical observation and routine cardiovascular assessment in this population.