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Objective: To look into the significant controversy existing about the safety and the dose of vit-amin D supplementation in pregnant women with a pandemic of vitamin D deficiency.
Search Method: We searched PubMed for information on Vitamin D, with special emphasis on reviews and studies regarding pregnancy.
Findings: Recent clinical research sheds doubt on the prevalent guidelines, by proposing that the circulating 25 hydroxy vitamin D should be 40-60 ng/ml (100-150 nmol) during pregnancy and a daily intake of 4000 IU vitamin D3 is required to attain this circulating level.
Conclusion: A search of the existing literature shows Vitamin D supplementation well above the current guidelines to be not just safe in pregnant patients, but also beneficial in preventing vari-ous adverse outcomes. There is a pressing need for further studies in this field in different populations, to establish accurate guidelines on Vitamin D levels in pregnancy.
Key words: Vitamin D, idiopathic hypercalcaemia.
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