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Special Article: Recommendation For use of Vitamin ‘D’ Treatment during Pregnancy
Author(s) Name:
Ghulam Rehman Mohyuddin
Rahat Qureshi
Address of Correspondence
Ghulam Rehman Mohyuddin, Medical Student, Aga Khan University, Karachi.


To look into the significant controversy existing about the safety and the dose of vit-amin D supplementation in pregnant women with a pandemic of vitamin D deficiency.
Search Method: We searched PubMed for information on Vitamin D, with special emphasis on reviews and studies regarding pregnancy.
Findings: Recent clinical research sheds doubt on the prevalent guidelines, by proposing that the circulating 25 hydroxy vitamin D should be 40-60 ng/ml (100-150 nmol) during pregnancy and a daily intake of 4000 IU vitamin D3 is required to attain this circulating level.
Conclusion: A search of the existing literature shows Vitamin D supplementation well above the current guidelines to be not just safe in pregnant patients, but also beneficial in preventing vari-ous adverse outcomes. There is a pressing need for further studies in this field in different populations, to establish accurate guidelines on Vitamin D levels in pregnancy.
Key words: Vitamin D, idiopathic hypercalcaemia.

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