Eclampsia is among the leading causes of maternal mortality which accounts for around 10% of all maternal deaths, according to National Surveys reviewed for this paper. Evaluation of the studies referred to, in this Review article, it became evident that the role of anticonvulsants is crucial for preventing and managing seizures during pregnancy. Some studies were critically evaluated for the choice between different drugs for treatment, much of the controversy over which having subsided, it became irrefutably evident that magnesium Sulphate (MgSO4) has greater efficacy in comparison with other drugs used for this purpose.
The objective for reviewing this topic was to find out as to why MgSO4 usage remains negligible in Pakistan, despite compelling evidence of its superiority. The extraction of information was from various studies including those in print or online or through the net, etc. There were National Surveys and Reports, National and International papers, product briefs, United Nations and WHO reports. The papers searched for the study were Randomised Trials, Systematic Reviews or Chochrane Reviews etc. etc. Some reports were from developed countries, while others were from developing countries world over, with some resource poor countries.
The Results of study showed that the PRIMARY BARRIERS to the use of MgSo4 in this country are, lack of National Priority and National Guidelines, lack of Education and training of concerned Health staff and shortage of supplies. It is concluded that for Pakistan, the challenge is the EVIDENCE BASED integration of use of MgSO4 into current clinical practice and procedures for the prevention and management of the disease.
Keywords: Eclampsia, Pre-eclampsia, Magnesium Sulphate, Pakistan.
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