Zonia Tanveer Nizami, Aalia Jadaan
|Address of Correspondence
Dr. Aalia Jadaan, Department of Obstetrics
& Gynaecology, Aziz FatimahTrust Hospital and Medical and
Dental College, Faisalabad
Objective: to investigate cause of primary amenorrhoea
among patients presenting at Aziz Fatimah Hospital, Faisalabad.
Study Design: descriptive cross sectional study.
Duration of Study: the study was conducted in
Department of Obstetrics & Gynecology, Aziz Fatimah Trust
Hospital and Medical and Dental College Faisalabad, for a duration
of 1 year from May, 2014 to April 2015.
Methodology: fifty six patients presenting with
primary amenorrhoea were enrolled for the study after history,
examination and necessary investigations. The patients of age
16 to 40 years who never had menstruation in life were included
in this study. Patients with surgical causes of amenorrhoea and
secondary amenorrhoea were excluded from the study. All the required
information was recorded on a predesigned Performa.
Results: the mean age of group was 19.46 ±
3.54 years. Majority of the patients 37(66.07%) had height in
the range of 126-150cm and 6 (10.71%) patients had height less
than 100cm. Weight of main bulk (35.71%) of patients was 46-50
In this sample 21 (37.50%) patients had infantile breast development,
the pubic hair was infantile in 20 (35.71%) patients and axilliary
hair was infantile in 17 (30.36%) patients. It was found that
main causes of the amenorrhoea in these patients were related
to anatomical defects in 25 (44%) patients. Followed by chromosomal
defects which were found in 17 (31%) patients and Hypothalamic-pituitary-ovarian
(HPO) axis defects were recorded in 10(18%) patients. In 4 (7%)
patients some other defects (like TB endometritis) were noted.
Conclusions: Though different treatment modalities
are available but outcome regarding regular menses and fertility
potential is not so satisfactory. With continuing advancement
of technologies of artificial reproduction there is still hope
for some patients with primary amenorrhoea to have their genetic
Key words: primary amenorrhoea, anatomical defects,
chromosomal defects, kuster-hauser syndrome.
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