Evaluating the Adequacy of Tissue using Manual Vacuum Aspiration (MVA) Versus Metal Curettage Method in Endometrial Sampling in Abnormal Uterine Bleeding

Abstract

Objective: To compare the adequacy of endometrial tissue obtained through Manual Vacuum Aspiration (MVA) versus Metal Curettage Method in females with abnormal uterine bleeding.

Methodology: This quasi-experimental study conducted at Obstetrics & Gynecology Department, Sir Ganga Ram Hospital, Lahore from April to October 2024. All 160 patients, presenting with AUB were included and were divided into two groups. Group A was undergoing endometrial sampling using MVA, while Group B was using sharp metal curettage. Samples from both groups were sent for histopathology, and adequacy was recorded. Females with suspected pelvic, infection or vaginal discharge, pre-malignant and malignant lesions of cervix, stenosis, uterine polyp, molar pregnancy, miscarriage, coagulopathy or history of coagulation disorder, heart diseases using anticoagulant or IUCD in situ were excluded. Post-stratification, both groups were compared for adequacy of sample by applying chi-square test in each stratum. P-value≤0.05 was considered as significant.All the data were analyzed in SPSS version 25.

Results: Total 160 patients, the mean age was 56.49 years, and the mean BMI was 28.39 kg/m². There were 68 cases of adequacy (46.9%) in Group A and 77 cases (53.1%) in Group B. There was a significant relationship of adequacy between study groups. (P<0.05).

Conclusion: The conclusion of the study that adequacy of endometrial sampling was significantly higher in the metal curettage group (Group B) compared to the MVA group (Group A). These findings suggest that metal curettage may be more effective in obtaining adequate samples for histopathological analysis.